Modelling and Simulation

Modelling Strategy including population pharmacokinetics (POPPK), exposure-response (ER) analysis, Physiologically-based pharmacokinetics (PBPK)
PKPD data analysis and modelling
Human dose prediction
Converting weight-base dosing (mg/kg) to flat dose (mg)
Paediatric extrapolation
Paediatric study design including optimal blood sampling timepoint
Dose Optimisation (eg. FDA Project Optimus for Oncology drugs)
Formulation development
Drug-drug interaction predictions